Impacts of different cytokine and chemokine polymorphisms in Pakistani asthmatics a case control study

Table 2 Association of Genotype and Allele Frequencies with Asthma Among Cases and Controls

SNP	sample	Minor Allele	Major Allele	Homozygotes Minor	Heterozygotes	Homozygotes Major	odds Ratio	95%CI
		T	C	TT	CT	CC
rs1800871	case	252	396	55	142	127	0.81	(0.62–1.05)
	control	155	197	33	89	54
		G	A	GG	AG	AA
rs1800896	case	179	473	30	119	177	1.38	(1.01–1.88)
	control	74	270	7	60	105
		T	C	TT	CT	CC
rs10173081	case	36	624	1	34	295	0.68	(0.41–1.14)
	control	28	332	1	26	153
		T	C	TT	CT	CC
rs1295685	case	206	450	36	134	158	1.06	(0.80–1.41)
	control	103	239	16	71	84
		T	C	TT	CT	CC
rs1800925	case	149	497	21	107	195	1.45	(1.04–2.02)
	control	59	285	3	53	116
		T	C	TT	CT	CC
rs1837253	case	199	455	28	143	156	0.85	(0.65–1.11)
	control	126	244	20	86	79
		T	C	TT	CT	CC
rs20541	case	191	449	35	121	164	0.97	(0.73–1.28)
	control	107	243	17	73	85
		G	C	GG	CG	CC
rs2289278	case	54	560	1	52	254	0.98	(0.61–1.56)
	control	30	304	4	22	141
		G	T	GG	GT	TT
rs1342326	case	104	546	14	76	235	0.92	(0.65–1.30)
	control	60	290	5	50	120
		G	A	GG	AG	AA
rs4986790	case	70	604	7	56	274	0.91	(0.60–1.36)
	control	42	328	1	40	144
		A	G	AA	AG	GG
rs3741240	case	259	393	53	153	120	0.94	(0.72–1.22)
	control	148	210	31	86	62
		G	A	GG	AG	AA
rs1801275	case	134	522	15	104	209	1.08	(0.78–1.50)
	control	66	278	10	46	116
		C	A	CC	AC	AA
rs1805011	case	39	605	3	33	286	1.68	(0.88–3.19)
	control	13	339	1	11	164
		G	A	GG	AG	AA
rs17809012	case	298	344	69	160	92	1.12	(0.86–1.46)
	control	149	193	34	81	56
		C	T	CC	CT	TT
rs1800825	case	22	636	1	20	308	1.29	(0.59–2.83)
	control	9	335	0	9	163

ISSN: 2054-9040