From: Pulmonary rehabilitation and cardiovascular risk in COPD: a systematic review
Author (Ref) | Subjects | Study design | Disease severity (mean FEV1% predicted) | CV measures | Detailed description of exercise and/or PR programme | CV response following exercise and/or PR programme. | p. value |
---|---|---|---|---|---|---|---|
Vivodtzev [5] | COPD patients (n = 17) | Prospective randomized trial | Trained, n = 10 (47 ± 20%) Untrained, n = 7 (54 ± 13%) | (c-r PWV) | Duration: 4 weeks. Session detail: 5 day/wk. (18 ± 8 to 30 ± 12 min exercise time) Intensity training endurance: Intensity was increased depending on the tolerance of the patients (to 6/10 on Borg scale). PWR increased from 38% ± 12% to 65% ± 12% of peak workload at the end of training. | ↓ aPWV in Trained group Baseline measurement (10.3 ± 0.7 m/s) After intervention (9.2 ± 0.8 m/s) | P = 0.001 |
Gale [6] | Controls (n = 20) COPD patients (n = 32) | Prospective cohort study | (45 ± 20%) | (aPWV) | Duration: 7 weeks. Duration/ sessions: 3 day/wk. (2.25 h exercise time) Intensity training endurance: The ISWT was used to set the intensity of exercise training at 60–70% VO2 peak. | ↓ aPWV Baseline measurement (9.8 ± 3.0 m/s) After intervention (9.3 ± 2.7 m/s) | P = <0.05 |
Vanfleteren [7] | Controls (n = 168) COPD patients (n = 162) | Prospective cohort study | (51.4 ± 17.4%) | (aPWV) | Duration: 8 weeks Duration/ sessions: 5 day/wk. (duration not specified) Intensity training endurance: Moderate to high intensity. The intensity was increased during the rehabilitation period, based on dyspnoea and fatigue symptom scores. | No change in aPWV Baseline measurement (10.7 ± 2.7 m/s) After intervention (10.9 ± 2.5 m/s) | P = 0.339 |