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Table 1 Criteria proposed by Spanish Respiratory Society for ACOS diagnosis

From: Ashtma-Chronic obstructive pulmonary disease overlap syndrome (ACOS): current evidence and future research directions

Major criteria

Minor criteria

Increase in FEV(1) ≥ 15% and ≥ 400 ml

High total IgE >100 UI/ml

Eosinophilia in sputum > 5%

Personal history of atopy

Personal history of asthma

Increase in FEV(1) ≥ 12% and ≥ 200 ml on 2 or more occasions