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Table 1 Summary of recommendations in new GOLD document comparing to old ones

From: GOLD 2017 recommendations for COPD patients: toward a more personalized approach

Topic

Previous Documents

2017 Document

Definition of COPD

“COPD, a common preventable and treatable disease, is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients”

Revised and simplified, to include the impact of respiratory symptoms and the role of lung tissue and airway abnormalities in the development of COPD

Disease development and progression

Genes, age, gender, low growth, exposure to particles, socioeconomic status, bronchial hyper-reactivity and infections are discussed

COPD development is further discussed, including new insights on lung development and on interactions of host factors and environmental exposures

COPD assessment tool

Based on the ABCD assessment tool, considering severity of airflow obstruction (FEV1), severity of symptoms (CAT, mMRC questionnaire) and history of exacerbations (>1)

ABCD assessment tool has been modified to utilize only respiratory symptoms and history of exacerbation

Role of spirometry

Provides fundamental information for the diagnosis, prognosis, the assessment of the disease, and the pharmacologic and non-pharmacologic management

The role has been revised. It is now fundamental in the diagnosis, prognosis, and discussion around non-pharmacologic treatment such as surgery

Non-pharmacologic therapies

Rehabilitation, oxygen therapy, ventilatory support, surgical treatment and end-of-life care are discussed

Evidence has been added on evaluation of inhaler technique, self-management, integrated care, and bronchoscopic interventions

Pharmacologic treatment

Treatment of stable COPD is individualized according to ABCD categories, with different options for each category

Shifts towards a more personalized approach (revised ABCD assessment tool, escalation and de-escalation strategies)

Comorbidities

Included in the definition of the disease, and discussed in a specific chapter

The complex issues of multimorbidity and polypharmacy have been added and discussed