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Table 7 Multivariate logistic regression analysis adusted odds ratio (95%CL) for antioxidant enzyme activities with COPD comorbidities: type 2 diabetes, pulmonary hypertension and cardiovascular

From: Altered antioxidant enzyme activity with severity and comorbidities of chronic obstructive pulmonary disease (COPD) in South Indian population

Variables

COPD

co-morbidities

OR

95% CI

p-values

Superoxide dismutase (U/mg protein)

T2D

1.99

-1.11 – 2.49

0.453

PHT

1.61

-0.57 – 1.53

0.374

CVD

2.32

-0.35 – 2.04

0.169

Catalase (U/mg protein)

T2D

1.98

-0.62 – 2.00

0.306

PHT

0.80

-1.14 – 0.70

0.642

CVD

1.77

-0.30 – 1.45

0.199

Glutathione s transferase (U/mg protein)

T2D

0.90

-1.39 – 1.18

0.873

PHT

1.41

-0.57 – 1.26

0.462

CVD

2.51

0.00 – 1.84

<0.049

Glutathione peroxidase (U/mg protein)

T2D

0.04

-6.60 – 0.53

<0.096

PHT

0.82

-1.12 – 0.72

0.677

CVD

0.63

-1.52 – 0.59

0.392

Glutathione reductase (U/mg protein)

T2D

0.58

-1.76 – 0.70

0.400

PHT

0.52

-1.67 – 0.40

0.228

CVD

0.57

-1.60 – 0.49

0.299

Total antioxidant status (μM Fe2+/l)

T2D

1.04

-1.07 – 1.16

0.934

PHT

1.26

-0.61 – 1.08

0.589

CVD

1.69

-0.45 – 1.50

0.291

  1. Significance of difference between erythrocyte antioxidant enzyme activities with COPD comorbidities: type 2 diabetes (T2D), pulmonary hypertension (PHT) and cardiovascular disease (CVD) p < 0.05; Border line significance: if p < 0.09; OR odds ratio, CI confidence interval