Table 6 Multivariate logistic regression analysis adusted odds ratio (95%CL) for erythrocyte anti-oxidation enzyme activities with severity of COPD according to GOLD stage classification, GOLD stage II, III and IV
Variables | GOLD stages | OR | 95% CI | p-values |
|---|---|---|---|---|
Superoxide dismutase (U/mg protein) | II | 0.97 | -0.05 – 0.01 | 0.173 |
III | 0.99 | -0.02 – 0.01 | 0.686 | |
IV | 1.00 | -0.00 – 0.02 | 0.292 | |
Catalase (U/mg protein) | II | 0.99 | -0.02 – 0.00 | 0.321 |
III | 0.99 | -0.01 – 0.00 | 0.551 | |
IV | 1.00 | -0.00 – 0.01 | 0.849 | |
Glutathione s transferase (U/mg protein) | II | 1.11 | 0.04 – 0.18 | <0.001 |
III | 1.01 | -0.01 – 0.05 | 0.284 | |
IV | 0.93 | -0.10 – 0.01 | <0.006 | |
Glutathione peroxidase (U/mg protein) | II | 1.02 | -0.00 – 0.05 | 0.082 |
III | 1.00 | -0.01 – 0.01 | 0.825 | |
IV | 0.98 | -0.03 – 0.00 | <0.034 | |
Glutathione reductase (U/mg protein) | II | 0.98 | -0.04 – 0.00 | 0.088 |
III | 0.99 | -0.01 – 0.00 | 0.507 | |
IV | 1.00 | -0.00 – 0.01 | 0.313 | |
Total antioxidant status (μM Fe2+/1) | II | 0.99 | -0.08 – 0.07 | 0.886 |
III | 0.97 | -0.07 – 0.02 | 0.274 | |
IV | 0.95 | -0.08 – 0.00 | <0.049 |