Altered antioxidant enzyme activity with severity and comorbidities of chronic obstructive pulmonary disease (COPD) in South Indian population

Table 3 Significant association of antioxidant enzyme activities in cases and controls

Study parameters	Healthy control n = 59	COPD n = 127
Superoxide dismutase (U/mg protein)	87.56 ± 0.48	77.34 ± 0.48***
Catalase (U/mg protein)	98.34 ± 0.94	72.77 ± 0.60***
Glutathione s transferase (U/mg protein)	42.05 ± 0.56	21.30 ± 0.33***
Glutathione peroxidase (U/mg protein)	63.77 ± 0.44	59.43 ± 0.50***
Glutathione reductase (U/mg protein)	77.08 ± 0.96	61.97 ± 0.60***
Total antioxidant status (μM Fe²⁺/l)	46.19 ± 0.27	41.64 ± 0.30***

Variables are expressed as mean ± SEM. Significance of difference between COPD patients compared to controls: ***P < 0.001

ISSN: 2054-9040