Variables | Controls | COPD |
---|---|---|
Mean ± SEM (n = 59) | Mean ± SEM (n = 127) | |
Age, years | 51.02 ± 0.27 | 60.10 ± 0.31** |
Male (n) | 38 (64.40) | 98 (77.16) |
Female (n) | 21 (35.59) | 29 (22.83) |
Weight (kg) | 65.32 ± 1.50 | 61.69 ± 0.32** |
Height (cms) | 157.12 ± 1.04 | 158.50 ± 0.26 |
BMI (kg/m2) | 26.43 ± 0.65 | 24.43 ± 0.20** |
Smoking Status | ||
Ex-smoker (n) | 13 (22.03) | 50 (39.37) |
current smoker (n) | 17 (28.81) | 32 (25.19) |
non-smoker (n) | 29 (49.15) | 45 (35.43 |
Spirometry parameter | ||
FEV1, % of predicted | 71.20 ± 1.26 | 36.21 ± 0.40*** |
FVC, % of predicted | 83.99 ± 1.06 | 50.15 ± 0.34*** |
FEV1/FVC, % of predicted | 97.56 ± 0.71 | 70.41 ± 0.46*** |
PaO2 (mmHg) | 57.51 ± 0.11 | |
SaO2 (%) | 90.62 ± 0.19 | |
COPD co-morbidities | ||
Type 2 diabetes (n) | 41 (32.28) | |
Pulmonary hypertension (n) | 52 (40.94) | |
Cardiovascular disease (n) | 27 (21.25) |