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Table 1 Comparison of baseline characteristics and change in trough FEV1 at week 12 in studies 1 and 2, and in the GLUCOLD study

From: Genetic evaluation of the effect of GLCCI1 rs37973 on corticosteroid response in chronic obstructive pulmonary disease

Variables

Study 1 (n = 94)

Study 2 (n = 308)

p value

GLUCOLD (n = 63)

Age, years

61.3 (0.9)

61.2 (0.5)

0.937

62.1 (1.02)

BMI, kg/m2

27.5 (0.6)

27.1 (0.3)

0.482

25.5 (0.48)

FEV1 at baseline, L

1.2 (0.04)

1.4 (0.03)

0.008

2.0 (0.05)

FEV1%pred at baseline

42.1 (1.1)

44.5 (0.8)

0.113

63.1 (1.1)

FEV1/FVC at baseline, %

48.3 (1.2)

46.1 (0.7)

0.111

50.8 (1.1)

Change in trough FEV1 as a % of predicted at Week 12

2.5 (0.8)

0.5 (0.4)

0.013

0.5 (0.8)

  1. p values shown are for differences between Studies 1 and 2
  2. Values are mean (standard error) unless otherwise stated
  3. BMI, body mass index, FEV 1 , forced expiratory volume in 1 s, FEV 1 %pred percent of predicted forced expiratory volume in 1 s, FVC forced vital capacity, GLUCOLD Groningen and Leiden Universities Study of Corticosteroids in Obstructive Lung Disease
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COPD Research and Practice

ISSN: 2054-9040

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