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Table 1 Comparison of baseline characteristics and change in trough FEV1 at week 12 in studies 1 and 2, and in the GLUCOLD study

From: Genetic evaluation of the effect of GLCCI1 rs37973 on corticosteroid response in chronic obstructive pulmonary disease

Variables Study 1 (n = 94) Study 2 (n = 308) p value GLUCOLD (n = 63)
Age, years 61.3 (0.9) 61.2 (0.5) 0.937 62.1 (1.02)
BMI, kg/m2 27.5 (0.6) 27.1 (0.3) 0.482 25.5 (0.48)
FEV1 at baseline, L 1.2 (0.04) 1.4 (0.03) 0.008 2.0 (0.05)
FEV1%pred at baseline 42.1 (1.1) 44.5 (0.8) 0.113 63.1 (1.1)
FEV1/FVC at baseline, % 48.3 (1.2) 46.1 (0.7) 0.111 50.8 (1.1)
Change in trough FEV1 as a % of predicted at Week 12 2.5 (0.8) 0.5 (0.4) 0.013 0.5 (0.8)
  1. p values shown are for differences between Studies 1 and 2
  2. Values are mean (standard error) unless otherwise stated
  3. BMI, body mass index, FEV 1 , forced expiratory volume in 1 s, FEV 1 %pred percent of predicted forced expiratory volume in 1 s, FVC forced vital capacity, GLUCOLD Groningen and Leiden Universities Study of Corticosteroids in Obstructive Lung Disease